Preheat oven to 375 °F (190 °C). Lightly coat a baking sheet with cooking spray and set aside.
In a mixing bowl, use your hands to combine salmon, bread crumbs, red onion, dijon mustard, mayonnaise, lemon juice, cayenne pepper, chili powder, salt, and pepper.
Shape mixture into 4 equally sized burger patties. Evenly space patties on baking sheet. Lightly spray the tops of burgers with cooking spray. Bake for 25-30 minutes or until golden brown.
When burgers are cooked through, remove from oven. Serve on buns with burger toppings if desired.
Nutrition summary
There are 223 calories in 1 serving of Skinny Salmon Burgers.